Uncertain thrombophilia markers
Thrombosis and Haemostasis, ISSN: 0340-6245, Vol: 115, Issue: 1, Page: 25-30
2016
- 39Citations
- 34Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations39
- Citation Indexes39
- 39
- CrossRef26
- Captures34
- Readers34
- 34
- Mentions1
- News Mentions1
- News1
Most Recent News
Clinical Investigation of Hereditary and Acquired Thrombophilic Factors in Patients with Venous and Arterial Thromboembolism
Introduction Thrombosis is a multi-etiological disease with several inherited and acquired risk factors both in the venous (VTE) and arterial (ATE) form.1,2 Though numerous thrombophilic
Review Description
The development of venous thromboembolism (VTE), which includes deep-vein thrombosis and pulmonary embolism, may be associated with inherited or acquired risk factors that can be measured in plasma or DNA testing. The main inherited thrombophilias include the plasma deficiencies of the natural anticoagulants antithrombin, protein C and S; the gain-of-function mutations factor V Leiden and prothrombin G20210A; some dysfibrinogenaemias and high plasma levels of coagulation factor VIII. Besides these established biomarkers, which usually represent the first-level laboratory tests for thrombophilia screening, a number of additional abnormalities have been less consistently associated with an increased VTE risk. These uncertain causes of thrombophilias will be discussed in this narrative review, focusing on their clinical impact and the underlying pathogenetic mechanisms. Currently, there is insufficient ground to recommend their inclusion within the framework of conventional thrombophilia testing.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84951335566&origin=inward; http://dx.doi.org/10.1160/th15-06-0478; http://www.ncbi.nlm.nih.gov/pubmed/26271270; http://www.schattauer.de/index.php?id=1214&doi=10.1160/TH15-06-0478; http://www.schattauer.de/index.php?id=5236&mid=24740&L=1; http://www.thieme-connect.de/DOI/DOI?10.1160/TH15-06-0478; https://dx.doi.org/10.1160/th15-06-0478; https://www.thieme-connect.de/products/ejournals/abstract/10.1160/TH15-06-0478
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