Gangrene is a type of tissue death caused by a lack of blood supply Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. The feet and hands are most commonly affected Certain types may present with a fever or seps...
2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
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Circulation, ISSN: 1524-4539, Vol: 135, Issue: 12, Page: e726-e779
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