Lack of Ser267Phe variant of sodium taurocholate cotransporting polypeptide among Moroccans regardless of hepatitis B virus infection status
BMC Infectious Diseases, ISSN: 1471-2334, Vol: 17, Issue: 1, Page: 99
2017
- 10Citations
- 18Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations10
- Citation Indexes10
- 10
- CrossRef5
- Captures18
- Readers18
- 18
Article Description
Background: The sodium taurocholate co-transporting polypeptide, encoded by SLC10A1, was identified as a functional receptor for hepatitis B virus (HBV). The objective of this study was to determine if there was an association of the Ser267Phe variant (rs2296651) with HBV infection status in Moroccan patients. Methods: Using a TaqMan 5' allelic discrimination assay, the Ser267Phe variant was genotyped in 286 chronic hepatitis B patients, 135 individuals with spontaneous clearance from HBV infection and 109 healthy controls negative for hepatitis B serological markers. Results: In this cohort, we detected only wild-type genotype (S267S) in all groups. This polymorphism was not associated with the HBV infection status in Moroccan patients. Conclusions: The S267F variant is absent among Moroccans regardless of chronic HBV infection status.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85010338076&origin=inward; http://dx.doi.org/10.1186/s12879-017-2214-2; http://www.ncbi.nlm.nih.gov/pubmed/28125961; http://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2214-2; https://dx.doi.org/10.1186/s12879-017-2214-2; https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2214-2
Springer Science and Business Media LLC
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