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Effects of astaxanthin on antioxidant capacity of golden pompano (Trachinotus ovatus) in vivo and in vitro

Fisheries and Aquatic Sciences, ISSN: 2234-1757, Vol: 20, Issue: 1
2017
  • 27
    Citations
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  • 34
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Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    27
    • Citation Indexes
      27
  • Captures
    34

Article Description

The objective of this research was to study the effect of astaxanthin (AST) on growth performance and antioxidant capacity in golden pompano (Trachinotus ovatus) both in vivo and in vitro. In the in vivo study, two diets were formulated with or without astaxanthin supplementation (D1 and D2; 0 and 200 mg/kg) to feed fish for 6 weeks. In the in vitro study, cells from hepatopancreas of golden pompano were isolated and four treatments with or without astaxanthin and HO supplementation were applied (control group: without both astaxanthin and HO treated; HO group: just with HO treated; HO+AST group: with both astaxanthin and HO treated; AST group: just with AST treated). Results of the in vivo study showed that weight gain (WG) and special growth rate (SGR) significantly increased with astaxanthin supplemented (P<0.05). Feed conversion ratio (FCR) of fish fed D2 diet was significantly lower than that of fish fed D1 diet (P<0.05). Hepatic total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of golden pompano fed D2 diet were significant higher than those of fish fed D1 diet (P<0.05). Superoxide dismutase (SOD) was significantly declined as astaxanthin was supplemented (P<0.05). Results of the in vitro study showed that the cell viability of HO group was 52.37% compared to the control group, and it was significantly elevated to 84.18% by astaxanthin supplementation (HO+AST group) (P<0.05). The total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of cell were significant decreased by oxidative stress from HO (P<0.05), but it could be raised by astaxanthin supplementation (HO vs HO+AST), and the malondialdehyde (MDA) was significant higher in HO group (P<0.05) and astaxanthin supplementation could alleviate the cells from lipid peroxidation injury. In conclusion, dietary astaxanthin supplementation can improve the growth performance of golden pompano. Moreover, astaxanthin can improve the golden pompano hepatic antioxidant capacity both in vivo and in vitro study by eliminating the reactive oxygen species.

Bibliographic Details

Jia jun Xie; Xu Chen; Jun Wang; Yun Wang; Qiang qiang Liu; Jin Niu

The Korean Society of Fisheries and Aquatic Science

Earth and Planetary Sciences; Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences

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