Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds.
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BMC genomics, ISSN: 1471-2164, Vol: 18, Issue: 1, Page: 565
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- Biochemistry, Genetics and Molecular Biology; Equine genomics; Whole genome sequence; SNP-tagging; SNP chip; Variant recalibration; SNP discovery; SNP informativeness; SNP validation; Linkage disequilibrium; Genetics and Genomics; Large or Food Animal and Equine Medicine
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To date, genome-scale analyses in the domestic horse have been limited by suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of the current SNP genotyping arrays. The recent availability of whole genome sequences has created the opportunity to develop a next generation, high-density equine SNP array.