Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke.
- Citation data:
Journal of biomedical science, ISSN: 1423-0127, Vol: 24, Issue: 1, Page: 25
- Publication Year:
- Medicine; Biochemistry, Genetics and Molecular Biology
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Estrogen plays an important role as an anti-inflammatory and neuroprotective agent in ischemic stroke. In this study, we analyzed the effect of a polygenic risk score (PRS) constructed using inflammatory genes and estradiol levels on the risk of ischemic stroke.