Childhood cancer risk in those with chromosomal and non-chromosomal congenital anomalies in Washington State: 1984-2013.

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PloS one, ISSN: 1932-6203, Vol: 12, Issue: 6, Page: e0179006

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10.1371/journal.pone.0179006; 10.1371/journal.pone.0179006.t002; 10.1371/journal.pone.0179006.g001; 10.1371/journal.pone.0179006.t003; 10.1371/journal.pone.0179006.t001; 10.1371/journal.pone.0179006.g002
Marlena S. Norwood; Philip J. Lupo; Eric J. Chow; Michael E. Scheurer; Sharon E. Plon; Heather E. Danysh; Logan G. Spector; Susan E. Carozza; David R. Doody; Beth A. Mueller; Jeffrey S. Chang Show More Hide
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Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences; Medicine; Cell Biology; Genetics; Molecular Biology; Neuroscience; Evolutionary Biology; Developmental Biology; Marine Biology; Cancer; Science Policy; Infectious Diseases; Computational Biology; childhood cancer; germ cell tumors; cancer types; estimate odds ratios; conclusions non-chromosomal anomalies; washington state cancer registries; anomaly; ci; childhood cancer risk; non-chromosomal anomalies; cns; hospital discharge data
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The presence of a congenital anomaly is associated with increased childhood cancer risk, likely due to large effects of Down syndrome and chromosomal anomalies for leukemia. Less is known about associations with presence of non-chromosomal anomalies.