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Frailty and Persistent Pain in Oncological Patients Undergoing Rehabilitation

The Journal of Frailty & Aging, ISSN: 2260-1341, Vol: 11, Issue: 3, Page: 286-290
2022
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Article Description

Pain is one of the most common symptoms among oncological patients and has a strong negative impact on quality of life. The aim of this study is to assess if frailty and polypharmacy are associated with persistent pain in oncological patients undergoing rehabilitation. Observational, prospective, longitudinal study. Data are from oncological patients admitted to the Oncological Rehabilitation Unit. Methods: Presence of pain, its intensity and characteristics were evaluated at the admission and after 7 days. A Frailty Index (FI) was computed from Comprehensive Geriatric Assessment (CGA) data. Among the 45 consecutively recruited patients (mean age 72 years, woman 44%), pain was present in 20 (44%) patients at the admission and 9 (20%) after 7 days of stay. Forty-one patients (92%) were taking more than 5 drugs at the admission (mean 9 drugs). The FI was normally distributed and descriptive statistics define our population as frail (mean 0.44; range 0.23–0.64). The FI was significantly associated with the presence of pain (OR 2.66; 95%CI 1.13–6.27, p=0.03) and its intensity after 7 days from the admission (β 4.24 95% CI 1.28–7.19, p=0.006), even after adjustment for potential confounders. Investigating frailty in cancer patients to implement multidisciplinary strategies could play an important role in improving persistent pain.

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