Protective effect of L-carnitine against oxidative damage caused by experimental chronic aflatoxicosis in quail (Coturnix Coturnix)
Acta Veterinaria Hungarica, ISSN: 0236-6290, Vol: 53, Issue: 3, Page: 319-324
2005
- 14Citations
- 15Captures
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Metrics Details
- Citations14
- Citation Indexes14
- 14
- CrossRef6
- Captures15
- Readers15
- 15
Article Description
This study was designed to evaluate the effect of L-carnitine supplementation on the plasma malondialdehyde (MDA) and whole blood reduced glutathione (GSH) concentrations in experimentally-induced chronic aflatoxicosis in quails. For this purpose, a total of 80 quails up to 8 weeks old were divided into four equal groups. Group I served as control, Group II was given L-carnitine at the dose of 200 mg/litre in the drinking water for 60 days, Group III was given 60 μg total aflatoxin/kg diet for 60 days, and Group IV was given both 60 μg total aflatoxin/kg diet and 200 mg L-carnitine/litre in the drinking water for 60 days. Aflatoxin treatment caused a significant increase in plasma MDA and a significant decrease in blood GSH concentrations. On the other hand, there was a significant decrease in plasma MDA and a significant increase in whole blood GSH in the L-carnitine-supplemented group. The present study demonstrated that L-carnitine brought about the inhibition of lipid peroxidation by enhancing antioxidant capacity in quails with chronic aflatoxicosis. © 2005 Akadémiai Kiadó.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=23844431918&origin=inward; http://dx.doi.org/10.1556/avet.53.2005.3.5; http://www.ncbi.nlm.nih.gov/pubmed/16156127; https://akjournals.com/doi/10.1556/avet.53.2005.3.5; http://www.akademiai.com/doi/abs/10.1556/AVet.53.2005.3.5; http://www.akademiai.com/index/L405V52116754774.pdf
Akademiai Kiado Zrt.
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