Modulation by progesterone of pain sensitivity to mechanical and ischemic stimuli in young and healthy women
Revista Brasileira de Ginecologia e Obstetricia, ISSN: 0100-7203, Vol: 30, Issue: 6, Page: 306-311
2008
- 8Citations
- 20,250Usage
- 16Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
PURPOSE: to investigate the relationship between pain perception (experimental pain threshold and tolerance, in response to ischemia and pressure) in young and healthy young women and female sexual hormone seric levels (estradiol and progesterone). METHODS: 18 volunteers have participated of this study, during three consecutive menstrual cycles. A pressure algometer and a manual dynamometer have been used to measure painful responses to pressure and ischemia algesic stimuli. Blood has been collected for assessment of both hormonal and painful variables, during three menstrual cycles, whose characterization was based on daily oral temperature record, a diary of the menstrual cycles with the onset and end of each cycle, and on estradiol and progesterone plasmatic levels. The average for the algesic variables measured has been compared by analysis of variance (ANOVA) and the Tukey-Kramer's post-test, among the menstrual cycle phases (follicular, periovulatory, early luteal, late luteal and menstrual). The Pearson's test has been used for correlation analysis between algesic and hormonal variables. Statistical significance has been defined as p<0.05. RESULTS: no significant change in pain parameters among the menstrual cycle phases has been observed. Nevertheless, there have been significant negative correlations between progesterone and ischemic threshold (r=-0.23; p<0.01), and pressure tolerance (r=-0.23; p<0.01) at the early luteal phase. CONCLUSIONS: these results indicate that the increase in progesterone levels correlates with a decrease of ischemic threshold and pressure tolerance, suggesting that progesterone plays a role in the pain modulation during the early luteal phase.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=51949101854&origin=inward; http://dx.doi.org/10.1590/s0100-72032008000600007; http://www.ncbi.nlm.nih.gov/pubmed/19142509; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032008000600007&lng=pt&nrm=iso&tlng=pt; http://www.scielo.br/pdf/rbgo/v30n6/07.pdf; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032008000600007&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-72032008000600007&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032008000600007; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-72032008000600007; https://dx.doi.org/10.1590/s0100-72032008000600007; https://www.scielo.br/j/rbgo/a/6vxQmTFgLFFtbpdBYf9cMSB/?lang=pt
FapUNIFESP (SciELO)
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know