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Mortality in US hemodialysis patients following exposure to Wildfire smoke

Journal of the American Society of Nephrology, ISSN: 1533-3450, Vol: 31, Issue: 8, Page: 1824-1835
2020
  • 37
    Citations
  • 0
    Usage
  • 67
    Captures
  • 4
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    37
  • Captures
    67
  • Mentions
    4
    • News Mentions
      3
      • News
        3
    • Blog Mentions
      1
      • Blog
        1

Most Recent News

Air Pollution From Wildfires Linked to Higher Death Rates in Patients with Kidney Failure

(HealthNewsDigest.com) - Washington, DC  — New research suggests that individuals with kidney failure may face a higher risk of dying prematurely if they’re exposed to

Article Description

Background Wildfires are increasingly a significant source of fine particulate matter (PM), which has been linked to adverse health effects and increased mortality. ESKD patients are potentially susceptible to this environmental stressor. Methods We conducted a retrospective time-series analysis of the association between daily exposure to wildfire PM and mortality in 253 counties near a major wildfire between 2008 and 2012. Using quasi-Poisson regression models, we estimated rate ratios (RRs) for all-cause mortality on the day of exposure and up to 30 days following exposure, adjusted for background PM, day of week, seasonality, and heat. We stratified the analysis by causes of death (cardiac, vascular, infectious, or other) and place of death (clinical or nonclinical setting) for differential PM exposure and outcome classification. Results We found 48,454 deaths matched to the 253 counties. A 10-mg/m increase in wildfire PM associated with a 4% increase in all-cause mortality on the same day (RR, 1.04; 95% confidence interval [95% CI], 1.01 to 1.07) and 7% increase cumulatively over 30 days following exposure (RR, 1.07; 95% CI, 1.01 to 1.12). Risk was elevated following exposure for deaths occurring in nonclinical settings (RR, 1.07; 95% CI, 1.02 to 1.12), suggesting modification of exposure by place of death. “Other” deaths (those not attributed to cardiac, vascular, or infectious causes) accounted for the largest portion of deaths and had a strong same-day effect (RR, 1.08; 95% CI, 1.03 to 1.12) and cumulative effect over the 30-day period. On days with a wildfire PM contribution .10 mg/m, exposure accounted for 8.4% of mortality. Conclusions Wildfire smoke exposure was positively associated with all-cause mortality among patients receiving in-center hemodialysis.

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