Comparison of estradiol and progesterone priming/antagonist/letrozole and microdose flare-up protocols for poor responders undergoing intracytoplasmic sperm injection
Gynecological Endocrinology, ISSN: 1473-0766, Vol: 30, Issue: 9, Page: 653-656
2014
- 11Citations
- 13Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations11
- Citation Indexes11
- 11
- CrossRef4
- Captures13
- Readers13
- 13
Article Description
Background: To compare the effect of the GnRH antagonist/letrozole/ gonadotropin protocol with the microdose GnRH agonist flare-up protocol in poor ovarian responders for intracytoplasmic sperm injection. Materials and methods: One hundred twenty-one consecutive patients suspected of having or with a history of poor ovarian response between January 2009 and June 2010, who were undergoing ICSI were enrolled. The microdose flareup (MF) protocol was used in 79 patients and the estradiol+progesterone/letrozole+gonadotropin and GnRH antagonist (EP/ALG) protocol was used in 42 patients. Results: Age of the patients, duration of infertility, basal FSH, the total gonadotropin consumption, duration of stimulation, E2 level on the day of hCG administration, the number of embryo transferred, the fertilization rate, implantation rate, clinical pregnancy rate and the live birth rate were not statistically different (p>0.05). Only the number of oocytes retrieved was significantly higher in the EP/LGA group (1.7±0.7 versus 2.6±0.6). Conclusion: The EP/LGA protocol has no significant improvement against the microdose flare-up protocol in poor responder patients. © 2014 Informa UK Ltd. All rights reserved.
Bibliographic Details
Informa UK Limited
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