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Evaluation of the Antibacterial Activity of Extracts of Ballota hirsuta Benth

Phytotherapie, ISSN: 1765-2847, Vol: 19, Issue: 5-6, Page: 341-347
2021
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In the present work, four flavonoic fractions were obtained from the raw leaves extracts of Ballota hirsuta Benth. The separation of flavonoids by thin layer chromatography (TLC) reveals the presence of flavonoids especially in the chloroform fraction and acetate. The results of HPLC show the presence of naringine in the n-BuOH fraction, sylibine and taxifoline in the acetate fraction. A considerable inhibitory activity of the four extracts was noticed on Escherichia coli ATCC 25922, and Staphylococcus aureus ATCC 13565. However, Pseudomonas aeruginosa ATCC 27835 has proven resistant to other bacteria, and this is due to the structure of its wall that gives it this resistance. The minimum inhibitory concentrations (MIC) vary from 0.25 to 2 mg/ml depending on the flavonoid extract and the microbial strain.

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