Association between leisure time physical activity and hdl-c in the elsa-brasil study participants: Are there any gender differences in the dose-response effect?
Arquivos Brasileiros de Cardiologia, ISSN: 1678-4170, Vol: 117, Issue: 3, Page: 494-500
2021
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Article Description
Background: High levels of high-density lipoprotein (HDL-C) are known for their protective effect against cardiovascular diseases and the regular practice of leisure time physical activity (LTPA) may be associated with their increase. Objective: To verify the existence of differences between genders in the dose-response effect regarding the association between LTPA and HDL-C in the ELSA-Brasil study cohort. Methods: Cross-sectional study with data from wave 2 of 13,931 participants of both genders (7,607 women) from the Longitudinal Study of Adult Health ELSA-Brasil. The LTPA was measured using the International Physical Activity Questionnaire (IPAQ) and classified into four categories: sedentary, low active, active and very active. The discriminatory power of LTPA at different intensities analyzed for high HDL-C was tested using ROC curves. Associations, adjusted for confounders between LTPA and HDL-C were analyzed by logistic regression. A 95% confidence interval was used. Results: A positive association, with a dose-response effect, was observed between LTPA and HDL-C in both men and women. With regard to intensity, only vigorous physical activity discriminated high HDL-C in men, while both walking and moderate and vigorous physical activity discriminated high HDL-C in women. Conclusions: LTPA shows a positive association with gradient dose-response and HDL-C, but in men, the association is not observed for those classified as physically unfit. In women, both walking intensity and moderate or vigorous physical activity can discriminate high HDL-C levels, whereas only vigorous intensity-exercise discriminate elevated HDL-C levels in men, demonstrating that males need to do more physical activity for this benefit to be observed.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85115783050&origin=inward; http://dx.doi.org/10.36660/abc.20200438; http://www.ncbi.nlm.nih.gov/pubmed/34231796; https://abccardiol.org/article/associacao-entre-atividade-fisica-no-tempo-livre-e-hdl-c-em-participantes-do-elsa-brasil-existem-diferencas-entre-homens-e-mulheres-no-efeito-dose-resposta/; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2021001100494&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2021001100494&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2021001100494; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2021001100494; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2021005009205&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2021005009205&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2021005009205; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2021005009205; https://dx.doi.org/10.36660/abc.20200438; https://abccardiol.org/wp-content/uploads/articles_xml/0066-782X-abc-117-03-0494/0066-782X-abc-117-03-0494.pdf
Sociedade Brasileira de Cardiologia
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