Pneumatosis cystoides intestinalis following alpha-glucosidase inhibitor treatment: A case report and review of the literature
World Journal of Gastroenterology, ISSN: 1007-9327, Vol: 14, Issue: 39, Page: 6087-6092
2008
- 74Citations
- 19Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations74
- Citation Indexes74
- 74
- CrossRef52
- Captures19
- Readers19
- 19
Article Description
A 69-year-old man was diagnosed as having myasthenia gravis (MG) in September 2004, and treated with thymectomy and prednisolone. He was then diagnosed as having steroid-induced diabetes mellitus, and received sulfonylurea (SU) therapy in May 2005. An alpha-glucosidase inhibitor (αGI) was added in March 2006, resulting in good glycemic control. He experienced symptoms of abdominal distention, increased flatus, and constipation in October 2007, and was admitted into our hospital in late November with hematochezia. Plain abdominal radiography revealed small linear radiolucent clusters in the wall of the colon. Computed tomography (CT) showed intramural air in the sigmoid colon. Colonoscopy revealed multiple smooth surfaced hemispherical protrusions in the sigmoid colon. The diagnosis of pneumatosis cystoides intestinalis (PCI) was made on the basis of these findings. As the αGI voglibose was suspected as the cause of this patient's PCI, treatment was conservative, ceasing voglibose, with fasting and fluid supplementation. The patient progressed well, and was discharged 2 wk later. Recently, several reports of PCI associated with αGI therapy have been published, predominantly in Japan where αGIs are commonly used. If the use of αGIs becomes more widespread, we can expect more reports of this condition on a global scale. The possibility of PCI should be considered in diabetic patients complaining of gastrointestinal symptoms, and the gastrointestinal tract should be thoroughly investigated in these patients. © 2008 The WJG Press. All rights reserved.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=59849126371&origin=inward; http://dx.doi.org/10.3748/wjg.14.6087; http://www.ncbi.nlm.nih.gov/pubmed/18932291; http://www.wjgnet.com/1007-9327/full/v14/i39/6087.htm; https://dx.doi.org/10.3748/wjg.14.6087; https://www.wjgnet.com/1007-9327/full/v14/i39/6087.htm
Baishideng Publishing Group Inc.
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