Design and Implementation of Real-Time Fluorescence Triple Correlation Spectroscopy Correlator Based on FPGA
Laser and Optoelectronics Progress, ISSN: 1006-4125, Vol: 61, Issue: 9
2024
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
To meet the requirements of multichannel fluorescence correlation spectroscopy with a wide dynamic range, a digital correlator based on field programmable gate array (FPGA) technology was designed and implemented. The hardware structure was designed and implemented using a register-level hardware description language. Based on the characteristics of photon pulse counting signals, the multi-sampling-time correlation and time-division multiplexing methods were used to calculate the correlation function, which substantially improved computing efficiency and optimized hardware resource utilization. The time-division multiplexing of cross correlation was extended to triple correlation, and the corresponding method was extended to adapt triple correlation. Ultimately, a real-time computing triple correlator based on FPGA was realized. The calculation method of symmetric normalization ensured the accuracy of the correlation function. The designed photon correlator was implemented based on a single Xilinx Zynq-7100 FPGA chip, which performed various functions, including the real-time correlation of three channels auto-correlation, three channels cross-correlation, and one channel triple correlation, with the time resolution of 40 ns and dynamic range of 1. 57 × 10
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