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Successful treatment of intralesional triamcilonon acetonide injection in keloid patients

Open Access Macedonian Journal of Medical Sciences, ISSN: 1857-9655, Vol: 7, Issue: 2, Page: 275-278
2019
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Article Description

AIM: Evaluation the effect of intralesional corticosteroid injection on keloid, at the National Hospital of Dermatology and Venereology from 1/2009 to 12/2009. METHODS: A group of 65 patients with keloid were randomly assigned into three groups. In the studied group, 33 patients were intralesionally injected 7.5 mg/1 cm2 of TCA. In the control group, TAC 32 patients were intralesionally injected 15 mg/1 cm2 of TCA. The result was evaluated basing on the criteria of Henderson (1998) and El-Tonsy (1996). RESULTS: In comparison between 2 groups, good to excellent improvement in the studied group was statistically higher than the control group (90.7% versus 68.7%; p < 0.05). After each injection, the thickness of the scar was reduced 1.24 ± 0.53 mm in the studied group and 0.81 ± 0.39 mm in the control group. The disappearance of pain and itching after treatment were 86.6% and 95.5% in the studied group and 78.1% and 80% in the control group (p > 0.05). Ulceration, acne and troublesome with menstrual cycles were sometimes were noted more frequently in the control group than in the studied group. CONCLUSION: Intralesional triamcinolone acetonide injection had a good result, and 7.5 mg/1 cm2 scar is the best dose for treatment of keloid.

Bibliographic Details

Huu, Nghi Dinh; Huu, Sau Nguyen; Thi, Xuan Le; Van, Thuong Nguyen; Minh, Phuong Pham Thi; Minh, Trang Trinh; Van, Tam Hoang; Cam, Van Tran; Huyen, My Le; Hau, Khang Tran; Gandolfi, Marco; Satolli, Francesca; Feliciani, Claudio; Tirant, Michael; Vojvodic, Aleksandra; Lotti, Torello

Scientific Foundation SPIROSKI

Medicine

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