Long menstrual cycle is associated with type 2 diabetes mellitus in Korean women
Diabetes and Metabolism Journal, ISSN: 2233-6079, Vol: 35, Issue: 4, Page: 384-389
2011
- 16Citations
- 61Captures
- 1Mentions
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Metrics Details
- Citations16
- Citation Indexes16
- 16
- CrossRef10
- Captures61
- Readers61
- 61
- Mentions1
- News Mentions1
- News1
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Article Description
Background: Long menstrual cycle is a risk factor for developing type 2 diabetes and cardiovascular disease in women. We aimed to evaluate the association between existing type 2 diabetes and oligomenorrhea before diagnosis of diabetes, and to observe the differences in this association among obese and non-obese Korean women. Methods: Patients with type 2 diabetes (n=118) and without any clinical evidence of abnormal glucose regulation (n=258) who attended the outpatient clinic of a university hospital and were over age 30. Patients self-reporting a menstrual cycle over 40 days during their 20s were defined as oligomenorrhea before diagnosis of diabetes. Obesity was defined as having a body mass index (BMI) over 25 kg/m . Results: The frequency of oligomenorrhea before diagnosis of diabetes was almost two-fold higher in women with type 2 diabetes than in the control group (16.1% vs. 8.5%, P=0.03). Oligomenorrhea was associated with type 2 diabetes after adjusting for age, BMI, systolic blood pressure, triglycerides, and high density lipoprotein cholesterol (odds ratio, 3.89; 95% confidence interval, 1.37 to 11.04). Among women with oligomenorrhea before diagnosis of diabetes, the frequency of type 2 diabetes was significantly higher in obese subjects than in their non-obese counterparts (90.9% vs. 30.0%, P=0.03). Conclusion: Having a long menstrual cycle could be a risk factor for the development of type 2 diabetes, especially in obese women. © 2011 Korean Diabetes Association.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864806546&origin=inward; http://dx.doi.org/10.4093/dmj.2011.35.4.384; http://www.ncbi.nlm.nih.gov/pubmed/21977458; http://e-dmj.org/journal/view.php?doi=10.4093/dmj.2011.35.4.384; http://synapse.koreamed.org/DOIx.php?id=10.4093/dmj.2011.35.4.384
Korean Diabetes Association
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