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Impact of treatment choice on the outcome of patients proposed for transcatheter aortic valve implantation

EuroIntervention, ISSN: 1774-024X, Vol: 6, Issue: 5, Page: 568-574
2010
  • 11
    Citations
  • 0
    Usage
  • 19
    Captures
  • 0
    Mentions
  • 1,440
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    11
  • Captures
    19
  • Social Media
    1,440
    • Shares, Likes & Comments
      1,440
      • Facebook
        1,440

Article Description

Aims: Transcatheter aortic valve implantation (TAVI) is a new option for patients with severe aortic stenosis at high surgical risk. We compared the clinical outcome of patients referred for TAVI and subsequently treated with TAVI, surgical aortic valve replacement (SAVR), balloon aortic valvuloplasty (BAV), or medical management (MM). Methods and results: All consecutive patients (n=166, EuroSCORE 24.9±13.9%) referred for TAVI to our two centres were enrolled in a prospective registry and were assigned to SAVR (n=21), TAVI with the CoreValve prosthesis (n=75), BAV (n=20), or MM (n=50) by a multi-specialty team. The primary endpoint was 6-month cardiac mortality. Patients undergoing BAV had a significantly higher EuroSCORE (33.6±15.9%; p=0.01). Median follow-up time was nine months (interquartile range 4.5-12.4 months). Six-month freedom from cardiac death was 81.0±8.6%, 92.0±3.1%, 72.9±10.5%, and 72.7±6.5% for SAVR, TAVI, BAV, and MM groups, respectively. Freedom from major cardiac and cerebrovascular events was 76.2±9.3%, 83.9±4.3%, 72.9±10.5%, and 65.6±6.8% for SAVR, TAVI, BAV, and MM groups, respectively. Conclusions: With respect to medical management and BAV, TAVI was associated with lower cardiac mortality at six months. Clinical outcome after TAVI was similar to that of less sick patients undergoing SAVR. © Europa Edition 2010. All rights reserved.

Bibliographic Details

De Carlo, Marco; Giannini, Cristina; Ettori, Federica; Fiorina, Claudia; Guarracino, Fabio; Curello, Salvatore; Scioti, Giovanni; Minzioni, Gaetano; Chizzola, Giuliano; Matteo, Diego; Petronio, A Sonia

Europa Digital & Publishing

Medicine

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