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Pentacam sensitivity and specificity in detecting occludable angles

European Journal of Ophthalmology, ISSN: 1120-6721, Vol: 22, Issue: 5, Page: 701-708
2012
  • 26
    Citations
  • 0
    Usage
  • 14
    Captures
  • 0
    Mentions
  • 14
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    26
    • Citation Indexes
      22
    • Policy Citations
      3
      • Policy Citation
        3
    • Clinical Citations
      1
      • PubMed Guidelines
        1
  • Captures
    14
  • Social Media
    14
    • Shares, Likes & Comments
      14
      • Facebook
        14

Article Description

Purpose. To assess the sensitivity and specificity of Pentacam measurements in detection of occludable angles and to provide cutoff values. Methods. Observational, single-center, cross-sectional study on 64 Caucasian eyes: 28 (43.7%) primary narrow angles or primary angle-closure glaucoma, and 36 (56.2%) controls: all subjects were evaluated and classified by gonioscopy (Shaffer classification). The following measurements have been considered: superior and inferior anterior chamber angle (ACA), temporal and nasal ACA, anterior chamber depth (ACD) using 5 value representation (central, superior, inferior, nasal, temporal), and anterior chamber volume (ACV). Validity of Pentacam parameters to detect patients in Shaffer 0 or I class was assessed by receiver operating characteristic (ROC) curves analysis; cutoffs were chosen as to maximize sensitivity and specificity. Results. All the considered Pentacam measures were statistically different between the 2 groups (p<0.0001). All Shaffer grade groups differed in all parameters (p<0.001), except for grade 0 and I, which did not differ in any. Area under the curve ROC analysis revealed high discriminant power of all Pentacam measures: ACA = 0.94; ACD = 0.91; ACD central = 0.89; and ACV = 0.89. Chosen cutoff values (ACA = 22.4°; ACD = 1.12 mm; ACD central = 1.93 mm; ACV = 84 mm) allowed correct classification of narrow angles. Conclusions. The study pointed out a high power of Pentacam AVA, ACV, and ACD in detecting occludable angles. Pentacam is simple to use, reliable, and noncontact, provides parameters in a short period, and represents a possible screening tool. © 2012 Wichtig Editore.

Bibliographic Details

Rossi, Gemma C M; Scudeller, Luigia; Delfino, Alessio; Raimondi, Marta; Pezzotta, Sara; Maccarone, Martina; Antoniazzi, Elena; Pasinetti, Gian Maria; Bianchi, Paolo Emilio

SAGE Publications

Medicine

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