You probably heard about Guava which is well known tropical fruit throughout the world. However, have you heard about its leaves which sh...
Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro.
- Citation data:
Journal of intercultural ethnopharmacology, ISSN: 2146-8397, Vol: 5, Issue: 2, Page: 122-30
- Publication Year:
- Pharmacology, Toxicology and Pharmaceutics; Medicine
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Elevated uric acid level, an index of gout resulting from the over-activity of xanthine oxidase (XO), increases the risk of developing hypertension. However, research has shown that plant-derived inhibitors of XO and angiotensin 1-converting enzyme (ACE), two enzymes implicated in gout and hypertension, respectively, can prevent or ameliorate both diseases, without noticeable side effects. Hence, this study characterized the polyphenolics composition of guava leaves extract and evaluated its inhibitory effect on XO and ACE in vitro.