Determination of cytomegalovirus glycoprotein b genotypes in different geographical regions and different patient groups in Turkey
Mikrobiyoloji Bulteni, ISSN: 0374-9096, Vol: 50, Issue: 1, Page: 53-62
2016
- 7Citations
- 18Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations7
- Citation Indexes7
- Captures18
- Readers18
- 11
Article Description
Cytomeg ilovirus (CMV), a common virus found all around the world, usually pauses asymptomatic infections in immunocompetent hosts, however it may lead to serious complicatior in immunodeficient patients and In the fetus. CMV is divided into four genotypes according to the pdymorphisms in UL55 gene that encodes for envelope glycoprotein B. Nucleotide polymorphisms of CK V gB gene can affect the cell tropism of the virus and host immune response and believed to have imp >rtant changes in the pathogenesis of CMV. The aim of this study was to determine the gB genotypes jf CMV isolates from different patiant groups selected from different regions of Turkey. A total of 136 clinical specimens from patients (66 lemale, 70 male; age range: 0-65 years, mean age: 24.03 ± 17.17) wli> were diagnosed to have CMV infection by polymerase chain reaction (PCR) and/or antigenemia tests, between 2001 -2014, in the medical school hospitals of Akdeniz, Ege, Istanbul Cerrahpasa and Erciyes Universities (located at Mediterrar ean, Aegean, northwest and central Anatolia regions, respectively), \yere included in the study. The patient group consisted of 80 renal transplant (RT) recipients, 35 stem
Bibliographic Details
Bilimsel Tip Publishing House
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