Accuracy of frozen sections for intraoperative diagnosis of complex atypical endometrial hyperplasia
Asian Pacific Journal of Cancer Prevention, ISSN: 2476-762X, Vol: 13, Issue: 5, Page: 1953-1956
2012
- 16Citations
- 7Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations16
- Citation Indexes16
- 16
- CrossRef8
- Captures7
- Readers7
Article Description
Objective: The purpose of this study was to correlate the histological diagnosis made during intraoperative frozen section (FS) examination of hysterectomy samples with complex atypical endometrial hyperplasia (CAEH) diagnosed with definitive paraffin block histology. Methods: FS pathology results of 125 patients with a pre-operative biopsy showing CAEH were compared retrospectively with paraffin block pathology findings. Results: Paraffin block results were consistent with FS in 78 of 125 patients (62.4%). The FS sensitivity and specificity of detecting cancer were 81.1% and 97.9%, with negative and positive predictive values of 76.7%, and 98.4%, respectively. Paraffin block results were reported as endometrial cancer in 77 of 125 (61.6%) patients. Final pathology was endometrial cancer in 45.3% patients diagnosed at our center and 76.9% for patients who had their diagnosis at other clinics (p=0.018). Paraffin block results were consistent with FS in 62.4% of all cases Consistence was 98.4% in patients who had endometrial cancer in FS. Conclusion: FS does not exclude the possibility of endometrial cancer in patients with the preoperative diagnosis of CAEH. In addition, sufficient endometrial sampling is important for an accurate diagnosis.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84872685918&origin=inward; http://dx.doi.org/10.7314/apjcp.2012.13.5.1953; http://www.ncbi.nlm.nih.gov/pubmed/22901153; http://koreascience.or.kr/journal/view.jsp?kj=POCPA9&py=2012&vnc=v13n5&sp=1953; http://ocean.kisti.re.kr/downfile/crosscheck/apocp/JAKO201226935182805.pdf; https://dx.doi.org/10.7314/apjcp.2012.13.5.1953; http://koreascience.or.kr/article/JAKO201226935182805.page
Asian Pacific Organization for Cancer Prevention
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