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Spindle cell carcinoma of the external auditory meatus with intracranial extension: Histological, immunohistochemical and electron microscopic evaluation

Acta Oto-Laryngologica, ISSN: 0001-6489, Vol: 127, Issue: 1, Page: 105-109
2007
  • 1
    Citations
  • 0
    Usage
  • 10
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    1
    • Citation Indexes
      1
  • Captures
    10

Article Description

We present a case of squamous spindle cell carcinoma of the external auditory meatus in a 38-year-old man. The tumour was extended to the inner ear, the temporal bone, the middle cranial fossa and the meningo-cerebral tissue. The surgical intervention of temporo-occipital craniotomy removed most of the neoplasia. At pathologic examination, the tumour showed an undifferentiated spindle cell pattern. Immunohistochemistry with a large antibody panel found a weak positivity only to EMA. The diagnosis was made when the electron microscopy showed rare junctional structures and tonofilaments. © 2007 Taylor & Francis.

Bibliographic Details

Quaranta, Antonio; Berardi, Paolo; Piscitelli, Domenico; Fiore, Maria Grazia; Calace, Antonello; Resta, Leonardo

Informa UK Limited

Medicine

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