PlumX Metrics
Embed PlumX Metrics

CHARACTERIZATION OF RADICAL ADDUCTS FORMED DURING PHOTOCHEMICAL SPIN TRAPPING IN LIPOSOMES

Photochemistry and Photobiology, ISSN: 1751-1097, Vol: 52, Issue: 2, Page: 323-331
1990
  • 8
    Citations
  • 0
    Usage
  • 3
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

There exists an urgent need to monitor radical reactions in biological membranes. With the exception of a few studies in model and natural membranes, most biological spin trapping reactions have been confined to homogeneous media. In the present work we have devised a methodology by which spin trapping reactions can be investigated in liposomes composed of a fully‐saturated phospholipid, dimyristoylphosphatidylcholine. Using photochemical spin trapping, we have detected and characterized the formation and partitioning of spin adducts in liposomes. Benzophenone (a lipid‐soluble photosensitizer) and benzoyl peroxide (a lipid‐soluble radical initiator) have been used to generate free radicals from hydrogen donors during photolysis in liposomes. Both water‐soluble and lipid‐soluble spin traps have been used to trap the radicals. Copyright © 1990, Wiley Blackwell. All rights reserved

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know