Filter-probe diffusion imaging improves spinal cord injury outcome prediction.
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Annals of neurology, ISSN: 1531-8249, Vol: 84, Issue: 1, Page: 37-50
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Diffusion-weighted imaging (DWI) is a powerful tool for investigating spinal cord injury (SCI), but has limited specificity for axonal damage, which is the most predictive feature of long-term functional outcome. In this study, a technique designed to detect acute axonal injury, filter-probe double diffusion encoding (FP-DDE), is compared with standard DWI for predicting long-term functional and cellular outcomes.