Filter-probe diffusion imaging improves spinal cord injury outcome prediction.

Citation data:

Annals of neurology, ISSN: 1531-8249, Vol: 84, Issue: 1, Page: 37-50

Publication Year:
2018
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PMID:
29752739
DOI:
10.1002/ana.25260
Author(s):
Skinner, Nathan P; Lee, Seung-Yi; Kurpad, Shekar N; Schmit, Brian D; Muftuler, L Tugan; Budde, Matthew D
Publisher(s):
Wiley
Tags:
Neuroscience; Medicine
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article description
Diffusion-weighted imaging (DWI) is a powerful tool for investigating spinal cord injury (SCI), but has limited specificity for axonal damage, which is the most predictive feature of long-term functional outcome. In this study, a technique designed to detect acute axonal injury, filter-probe double diffusion encoding (FP-DDE), is compared with standard DWI for predicting long-term functional and cellular outcomes.