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Gold-induced severe aplastic anemia: Medullary autologous reconstitution after immunosuppression. An observation

Haematologica, ISSN: 0390-6078, Vol: 70, Issue: 1, Page: 53-55
1985
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Article Description

The authors have observed a case of gold-induced severe aplastic anemia in which a complete reponse to immuno-suppressive treatment (high dose bolus 6-methylprednisolone) was obtained. The observation suggests that bolus 6-methylprednisolone is able to induce medullary autologous reconstitution in gold-induced severe aplastic anemia. The authors discuss the mechanism of myelotoxicity and the indications for immunosuppressive treatment. This case emphasizes the probable immune-mediated pathogenesis of gold-induced aplastic anemia.

Bibliographic Details

I. Iori; C. Salvarani; S. Prandi; P. Macchioni; G. Filippi; G. Del Din

Medicine

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