Dissection of the antigenic determinants expressed on the cell surface of rsv‐transformed fibroblasts by monoclonal antibodies
International Journal of Cancer, ISSN: 1097-0215, Vol: 29, Issue: 4, Page: 477-481
1982
- 7Citations
- 8Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations7
- Citation Indexes7
- CrossRef3
- Captures8
- Readers8
Article Description
Fusion of P3/X63‐Ag8 mouse myeloma cells with splenocytes obtained from mice hyperimmunized with a BHK hamster fibroblast line transformed by an envstrain of Rous sarcoma virus (RSV) resulted in the production of antibody‐secreting hybridomas. Seven hybrid clones secreted antibodies binding to RSV‐transformed BHK fibroblasts but not to the parental control non‐transformed line. The antibodies produced by three of these clones did identify antigenic determinants expressed also on BHK cells transformed by SV40. The antibodies produced by four other clones reacted specifically with cells transformed by RSV but not with cells productively infected by the transformation‐defective Rous‐associated virus‐1; one of these reacted with RSV‐transformed hamster cells only, three others identified antigenic determinants common to RSV‐ transformed cells of different animal species. These data give further support to the idea that RSV‐transformed cells express a cell‐surface antigen, specific for transformation, the expression of which is controlled by the transforming src gene, and that the specificities carried on it follow a complex pattern, arising from the interaction between antigenic determinants of cellular and viral origin. Copyright © 1982 Wiley‐Liss, Inc., A Wiley Company
Bibliographic Details
Wiley
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