Specific binding of dl‐cloprostenol and d‐cloprostenol to PG F receptors in bovine corpus luteum and myometrial cell membranes
Journal of Veterinary Pharmacology and Therapeutics, ISSN: 1365-2885, Vol: 17, Issue: 6, Page: 455-458
1994
- 29Citations
- 17Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations29
- Citation Indexes29
- 29
- CrossRef18
- Captures17
- Readers17
- 17
Article Description
Prostaglandin F receptors (PGF Rs) were measured in bovine corpus luteum and myometrial cell membranes using a radiometric method. The inhibition of labelled PGF binding exerted by d‐cloprostenol, dl‐cloprostenol, PGF and PGE (l0– M to 10 M) was evaluated in vitro. Results strongly suggest that cloprostenol binding to PGFRs is stereospecific. d‐Cloprostenol and PGF were equipotent, about 150 times more potent than d‐cloprostenol (P < 0.05) and approximately 280 times more potent than PGE, (P < 0.05) in inhibiting [3H]PGF binding to corpus luteum cell membranes. Such differences were less evident in myometrial cell membranes, where d‐cloprostenol and PGF were about 10 times more potent than d‐cloprostenol (P < 0.05) and approximately 95 times more potent than PGE (P < 0.05). Copyright © 1994, Wiley Blackwell. All rights reserved
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0028556933&origin=inward; http://dx.doi.org/10.1111/j.1365-2885.1994.tb00277.x; http://www.ncbi.nlm.nih.gov/pubmed/7707491; https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2885.1994.tb00277.x; https://dx.doi.org/10.1111/j.1365-2885.1994.tb00277.x
Wiley
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