Propafenone-induced liver injury: Report of a case and review of the literature
Gastroenterology, ISSN: 0016-5085, Vol: 104, Issue: 5, Page: 1524-1526
1993
- 22Citations
- 1Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations22
- Citation Indexes22
- 22
- CrossRef16
- Captures1
- Readers1
Article Description
A case of an acute cholestatic syndrome associated with use of the antiarrhythmic drug propafenone is reported here. The close time relationship between the administration of the drug and the acute onset of the liver damage, the histological findings, and the reappearance of biochemical signs of liver dysfunction upon rechallenge with the same medication strongly suggest that propafenone was involved in the pathogenesis of this syndrome. Although rare, hepatotoxicity from this widely used antiarrhythmic medication should be kept in mind in the differential diagnosis of sudden cholestatic syndrome of obscure origin.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/001650859390365J; http://dx.doi.org/10.1016/0016-5085(93)90365-j; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027216781&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/8482464; http://linkinghub.elsevier.com/retrieve/pii/001650859390365J; http://api.elsevier.com/content/article/PII:001650859390365J?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:001650859390365J?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/001650859390365J; http://dx.doi.org/10.1016/0016-5085%2893%2990365-j; https://dx.doi.org/10.1016/0016-5085%2893%2990365-j
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