Protocol for a randomised, double-masked, sham-controlled phase 4 study on the efficacy, safety and tolerability of intravitreal aflibercept monotherapy compared with aflibercept with adjunctive photodynamic therapy in polypoidal choroidal vasculopathy: the ATLANTIC study.

Citation data:

BMJ open, ISSN: 2044-6055, Vol: 7, Issue: 8, Page: e015785

Publication Year:
2017
Usage 5
Abstract Views 5
Repository URL:
http://hdl.handle.net/10400.4/2124
PMID:
28851779
DOI:
10.1136/bmjopen-2016-015785
Author(s):
Marques, João Pedro, Farinha, Cláudia, Costa, Miguel Ângelo, Ferrão, Ângela, Nunes, Sandrina, Silva, Rufino
Publisher(s):
BMJ
Tags:
Fotoquimioterapia, Receptores de Factores de Crescimento do Endotélio Vascular, Acuidade Visual, Doenças da Coróide, Pólipos
article description
The purpose of this study is to compare the efficacy and safety of intravitreal aflibercept (IVA) with sham photodynamic therapy (sPDT) versus IVA with verteporfin PDT (vPDT) in a Caucasian population with treatment-naive polypoidal choroidal vasculopathy (PCV), enrolling into a treat and extend (T&E) regimen.

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