Protocol for a randomised, double-masked, sham-controlled phase 4 study on the efficacy, safety and tolerability of intravitreal aflibercept monotherapy compared with aflibercept with adjunctive photodynamic therapy in polypoidal choroidal vasculopathy: the ATLANTIC study.
- Citation data:
BMJ open, ISSN: 2044-6055, Vol: 7, Issue: 8, Page: e015785
- Publication Year:
- Fotoquimioterapia, Receptores de Factores de Crescimento do Endotélio Vascular, Acuidade Visual, Doenças da Coróide, Pólipos
The purpose of this study is to compare the efficacy and safety of intravitreal aflibercept (IVA) with sham photodynamic therapy (sPDT) versus IVA with verteporfin PDT (vPDT) in a Caucasian population with treatment-naive polypoidal choroidal vasculopathy (PCV), enrolling into a treat and extend (T&E) regimen.