Downbeat nystagmus elicited by eyelid closure.

Citation data:

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, ISSN: 1536-5166, Vol: 34, Issue: 4, Page: 350-3

Publication Year:
2014
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Repository URL:
http://hdl.handle.net/10400.4/2155
PMID:
24667774
DOI:
10.1097/wno.0000000000000123
Author(s):
Lemos, João; Pereira, Daniela; Amorim, Margarida; Santiago, Beatriz; Paiva, António; Cunha, Luís
Publisher(s):
Ovid Technologies (Wolters Kluwer Health)
Tags:
Medicine; Movimentos Oculares; Nistagmo Patológico; Área Tegmentar Ventral
article description
We describe a patient with downbeat nystagmus (DBN) evoked only by eye closure. Brain and spinal cord magnetic resonance imaging revealed a T2 paramedian lesion in the left lower basis pontis and other white matter lesions consistent with multiple sclerosis. One potential mechanism for DBN in this case involves transverse ephaptic spread of excitation from areas that subserve coordinated lid closure to the decussating ventral tegmental tract.