Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis.
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Biochimica et biophysica acta, ISSN: 0006-3002, Vol: 1850, Issue: 2, Page: 373-84
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- Biochemistry, Genetics and Molecular Biology; Flt1; VEGF receptor inhibitor; Calycosin; Zebrafish; Endothelial cell; Molecular docking; Medical Biochemistry
The role of Kdr (VEGFR-2/Flk-1) in vascular formation has been well described, but the role of Flt1 (VEGFR-1) is not well studied and is generally considered as a decoy receptor for trapping VEGF.