Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA).

Citation data:

European journal of heart failure, ISSN: 1879-0844, Vol: 17, Issue: 3, Page: 313-9

Publication Year:
2015
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Repository URL:
https://researchbank.acu.edu.au/fhs_pub/6065
PMID:
25639660
DOI:
10.1002/ejhf.237
Author(s):
Haver, Vincent G.; Leach, Irene Mateo; Kjekshus, John; Fox, Jayne C.; Wedel, Hans; Wikstrand, John; de Boer, Rudolf A.; van Gilst, Wiek H.; McMurray, John J. V.; van Veldhuisen, Dirk J.; van der Harst, Pim Show More Hide
Publisher(s):
Wiley-Blackwell; John Wiley and Sons Ltd
Tags:
Medicine; leucocyte telomere length; ageing; heart failure; healthy ageing; Cardiology
article description
Leucocyte telomere length is considered a marker of biological ageing and has been suggested to be shorter in patients with CAD and heart failure compared with healthy controls. The aim of this study was to determine whether telomere length is associated with clinical outcomes in patients with ischaemic heart failure and whether this association is superior to chronological age as defined by date of birth.