CD30+ reversible lymphoid dyscrasia (pseudolymphoma) following HIDA scintigraphy and the [Ring1]-[Ring2]-[C=O] generalized structure hypothesis.

Citation data:

Journal of the American Academy of Dermatology, ISSN: 1097-6787, Vol: 68, Issue: 3, Page: e99-101

Publication Year:
2013
Usage 25
Abstract Views 25
Captures 0
Readers 0
Citations 1
Citation Indexes 1
Repository URL:
http://scholarsmine.mst.edu/chem_facwork/1433
PMID:
23394929
DOI:
10.1016/j.jaad.2012.09.044
Author(s):
Rader, Ryan K.; Stoecker, William V.; Hinton, Kristen A.; Malone, Janine C.; Schuman, Thomas P.
Publisher(s):
Elsevier BV; Elsevier
Tags:
Medicine; Chemistry
article description
To the Editor: Eighteen days after hepatobiliary iminodiacetic acid (HIDA) scintigraphy, an 81-year-old woman presented with pruritic, painful, discrete, tender papules in a generalized distribution (Fig 1). She noted onset of the eruption shortly after the HIDA scan. Biopsy specimen of 2 papules from the right thigh showed an infiltration of mitotically active lymphocytes (Fig 1, top inset) confined to the upper dermis. The lymphocytes were predominantly CD3+ T cells; occasional scattered CD20+ B cells were present. CD4 and CD8 were present in an approximately 2:1 ratio, and both cell types were noted within the epidermis. Small aggregates of large CD3+/CD30+ lymphocytes were present, comprising less than 25% of the lymphoid population (Fig 1, bottom inset). The histopathology and immunostaining supported a diagnosis of CD30+ plasma cell dyscrasia (pseudolymphoma).