Synthesis of a Bipyridine Ligand for Metal-Triggered Supramolecular Polymers

Citation data:

Vol: 7, Issue: 1

Publication Year:
2018
Usage 41
Abstract Views 21
Downloads 20
Repository URL:
https://via.library.depaul.edu/depaul-disc/vol7/iss1/6
Author(s):
Gould, Andrew D
Tags:
Supramolecular polymers; synthesis; metal-chelator; bipyridine; Organic Chemistry; Polymer Chemistry
article description
Intermolecular forces, such as H-bonding, ionic interactions and metal chelation between small molecules, can lead to the assembly of higher-order supramolecular nanostructures. A metal chelator, 2-(Pyridin-2-yl) pyridine-5-carboxylic Acid (a bipyridine derivative), is expected to aid in the formation of supramolecular structures as part of amphiphilic molecules that self-assemble in solution in the presence of metal ions. The bipyridine ligand currently under synthesis can be prepared through a five-step synthesis scheme. The second reaction of this synthesis (the coupling of two pyridine rings) resulted in a combination of the desired 1,2,5-isomer, as well as an unforeseen 1,2,3-isomer. Future research will therefore examine how this reaction can be improved, or circumnavigated altogether, so as to maximize the yield of the 1,2,5-configuration. Once properly synthesized, the bipyridine will be incorporated into an amphiphilic scaffold and assessed for its ability to form supramolecular polymers in the presence of various divalent metal cations.