Finding the missing link in single use fermentation line : Evaluation of single use bioreactors for aerobic bacteria
2016
- 52Usage
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Usage52
- Abstract Views52
Abstract Description
The application of single use technologies for the bioproduction represents a major technology innovation advance. Single use bioreactors for cell culture have been largely implemented for manufacturing, providing significant flexibility, costs reduction and fast implementations. In contrast, few technologies are available for aerobic bacterial fermentation mainly due to limitations for oxygen and heat transfer. Like clinical products derived from bacterial expression system still represent a significant number of bio therapeutics/vaccines, some investigations have been performed in Sanofi Pasteur to evaluate new single use fermenters suitable for aerobic process and matching to clinical manufacturing scale. The 300L HyPerforma SUF (ThermoFisher) has been evaluated with an E.coli strain to produce a recombinant protein and with yeast.
Bibliographic Details
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know