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Development of scalable downstream processing platform for HEK293SF cell-based influenza vaccine production

2022
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Abstract Description

Background: Research efforts during recent decades have demonstrated the suitability of mammalian cell culture platform for influenza vaccine production. Certainly, the potential of this system for a large-scale continuous vaccine manufacturing will enable a faster response to pandemic comparing with traditional egg-based production. Even though great advances have been achieved on the upstream processing of mammalian cell culture produced influenza vaccines, the downstream processing and quality of final product have still room for improvement or is still in development.Please click Download on the upper right corner to see the full abstract.

Bibliographic Details

Amine Kamen; Xingge Xu; Zeyu Yang; Irene González Domínguez; Cécile Toussaint; Alice Bernier; Alina Venereo Sanchez; Omar Famos; Cristina Aglaia Alves Tottoli e Silva

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