Presence of monoclonal free light chains in the serum predicts risk of progression in monoclonal gammopathy of undetermined significance
British Journal of Haematology, ISSN: 0007-1048, Vol: 127, Issue: 3, Page: 308-310
2004
- 67Citations
- 1Usage
- 22Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations67
- Citation Indexes67
- 67
- CrossRef42
- Usage1
- Abstract Views1
- Captures22
- Readers22
- 22
Article Description
We hypothesized that the presence of monoclonal free light chains (FLC) in the serum of patients with monoclonal gammopathy of undetermined significance (MGUS) is a marker of clonal evolution and a risk factor for progression. Forty-seven patients with MGUS and documented progression to myeloma or related malignancy were compared with 50 age- and gender-matched patients with MGUS and no evidence of progression after 5 or more years of follow-up. The presence of an abnormal kappa/lambda FLC ratio in the serum was associated with a higher risk of MGUS progression (relative risk 2.5; 95% confidence interval: 1.6-4.0; P < 0.001).
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=7944231889&origin=inward; http://dx.doi.org/10.1111/j.1365-2141.2004.05169.x; http://www.ncbi.nlm.nih.gov/pubmed/15491291; https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2004.05169.x; https://dc.etsu.edu/etsu-works/18642; https://dc.etsu.edu/cgi/viewcontent.cgi?article=19908&context=etsu-works
Wiley
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