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All-or-none solvent-induced transitions between native, molten globule and unfolded states in globular proteins

Folding and Design, ISSN: 1359-0278, Vol: 1, Issue: 2, Page: 117-122
1996
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Article Description

It has long been established that temperature-induced melting of small globular proteins is an all-or-none transition. Little was known, however, about the degree of cooperativity of denaturant-induced transitions in proteins, especially in those cases in which the proteins unfold through the molten globule state.

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