Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO): A Novel Retinal Metabolic Biomarker for Multiple Sclerosis
2025
- 28Usage
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
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- Usage28
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- Downloads12
Poster Description
Introduction- Fluorescence lifetime imaging ophthalmoscopy (FLIO, Heidelberg Engineering, Figures 1 and 2), a novel in vivo retinal imaging biomarker, generates fluorescence decay lifetimes in 2 spectral channels corresponding to the following metabolic processes:- Short Spectral Channel (SSC): 498 – 560 nm Corresponds to macular pigment, flavin adenine dinucleotide (FAD) and oxidative phosphorylation. - Long Spectral Channel (LSC): 560 – 720nm Corresponds to predominantly lipofuscin and lysosomal function - Based upon animal experimental models and clinical data, mitochondrial dysfunction has a role in the pathophysiology of both inflammatory and degenerative components of Multiple Sclerosis
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