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Spx1, a novel X-linked homeobox gene expressed during spermatogenesis.

Page: 87-98
1997
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Article Description

Spx1, a novel mouse homeobox gene, encodes a homeodomain characteristic of the paired-like class of homeobox genes and has been mapped to the distal end of the X chromosome. Northern blot hybridization of adult tissues detected high levels of a single Spx1 transcript in the testis. Further analysis by in situ hybridization revealed predominant Spx1 expression within the spermatogonia/preleptotene spermatocytes and round spermatids of spermatogenic stages IV-VII. These expression data suggest SPX1 may play a role in the regulation of spermatogenesis.

Bibliographic Details

W W Branford; G Q Zhao; M T Valerius; M Weinstein; E H Birkenmeier; L B Rowe; S S Potter

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