Cognition-Enhancing Doses of Methylphenidate Preferentially Increase Prefrontal Cortex Neuronal Responsiveness
Biological Psychiatry, ISSN: 0006-3223, Vol: 64, Issue: 7, Page: 626-635
2008
- 101Citations
- 206Usage
- 118Captures
- 1Mentions
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations101
- Citation Indexes101
- 101
- CrossRef96
- Usage206
- Downloads201
- Abstract Views5
- Captures118
- Readers118
- 118
- Mentions1
- References1
- 1
Article Description
Despite widespread use of low-dose psychostimulants for the treatment of attention-deficit/hyperactivity disorder (ADHD), the neural basis for the therapeutic actions of these drugs are not well understood. We recently demonstrated that low-dose methylphenidate (MPH) increases catecholamine efflux preferentially within the prefrontal cortex (PFC), suggesting that the PFC is a principal site of action in the behavioral-calming and cognition-enhancing effects of low-dose psychostimulants. To understand better the neural mechanisms involved in the behavioral actions of low-dose stimulants, this study examined the effects of low-dose MPH on the discharge properties of individual and ensembles of PFC neurons.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0006322308006033; http://dx.doi.org/10.1016/j.biopsych.2008.04.037; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=49949098981&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/18585681; https://linkinghub.elsevier.com/retrieve/pii/S0006322308006033; https://rdw.rowan.edu/som_facpub/50; https://rdw.rowan.edu/cgi/viewcontent.cgi?article=1049&context=som_facpub
Elsevier BV
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