PlumX Metrics
Embed PlumX Metrics

Cardiac Resynchronization Therapy and Clinical Outcomes in Continuous Flow Left Ventricular Assist Device Recipients

J Am Heart Assoc, Vol: 7, Issue: 12
2018
  • 0
    Citations
  • 42
    Usage
  • 0
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

BACKGROUND: Many patients with heart failure continue cardiac resynchronization therapy (CRT) after continuous flow left ventricular assist device (CF-LVAD) implant. We report the first multicenter study to assess the impact of CRT on clinical outcomes in CF-LVAD patients.METHODS AND RESULTS: Analysis was performed on 488 patients (58±13 years, 81% male) with an implantable cardioverter defibrillator (ICD) (n=223) or CRT-D (n=265) who underwent CF-LVAD implantation at 5 centers from 2007 to 2015. Effects of CRT on mortality, hospitalizations, and ventricular arrhythmia incidence were compared against CF-LVAD patients with an ICD alone. Baseline differences were noted between the 2 groups in age (60±12 versus 55±14,CONCLUSIONS: In this large, multicenter CF-LVAD cohort, continued CRT was not associated with improved survival, hospitalizations, incidence of ventricular arrhythmia and ICD therapies, and was related to a significantly higher number of pulse generator changes.

Bibliographic Details

Rakesh Gopinathannair; Henri Roukoz; Adarsh Bhan; Ashwin Ravichandran; Mustafa M Ahmed; Dmitry Familtsev; Geetha Bhat; Jennifer A Cowger; Munazzah Abdullah; Chirag Sandesara; Rahul Dhawan; Emma J Birks; Jaimin R Trivedi; Mark S Slaughter

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know