Use of glucagon-like peptide-1 receptor agonistsfor pediatric patients with obesity and diabetes: the providers' perspectives
2021
- 22Usage
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
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- Usage22
- Abstract Views22
Article Description
Introduction: Glucagon-like peptide-1 receptor agonists(GLP-1RA) have been widely used in adults with type 2 diabetes (T2D) and obesity. We sought to evaluate the experience of pediatric endocrinology providers with GLP-1RA and factors that guide them on whether and how to prescribe these medications. Methods: We surveyed themembers of the Pediatric Endocrine Society regarding the use of GLP-1RA in their practice. Results: The respondents (n=102)were predominantly from academic centers (84%)and 75%reported using GLP-1RA in pediatric patients, mostly to treat T2D and obesity. Patient tolerance for the medication was reported to be the driving factor determining the duration of treatment. Gastrointestinal side effects were observed more commonly than local reactions or elevation of pancreatic enzymes. Lack of clinical experience was reported to be a major barrier for prescribing GLP-1RA, particularly among those with more than 5 years of clinical experience. Finally, liraglutide was used more often (93%) than other GLP-1RA. Conclusions: The use of GLP-1RAhas increased in pediatric patients. Recent FDA approval of liraglutide for pediatric obesity will likely further increase its prescription rate. Providers should be vigilant about side effects and adjust the doses of GLP-1RA accordingly. More efforts should be made by professional societies to educate pediatric endocrinology providers about the proper use of GLP-1RA and enhance their confidence in prescribing these medications. This article is protected by copyright. All rights reserved. Keywords: GLP-1RA; GLP1; obesity; type 1 diabetes; type 2 diabetes.
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