Beta 1 Adrenergic Receptor Polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo Populations of Mexico

Citation data:

Human Biology, ISSN: 0018-7143, Vol: 77, Issue: 4, Page: 9

Publication Year:
2005
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Abstract Views 65
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Repository URL:
https://digitalcommons.wayne.edu/humbiol/vol77/iss4/9
Author(s):
Fragoso, Jose Manuel; Rodriguez-Perez, Jose Manuel; Perez-Vielma, Nadia; Martinez-Rodriguez, Nancy
Tags:
BETA 1 ADRENERGIC RECEPTOR; MESTIZOS; TEENEK; MAYOS; MEXICAN POPULATIONS.
article description
The 1 adrenergic receptor genotypes (Ser49Gly and Arg389- Gly) were determined in 190 individuals from 3 Mexican populations. Mestizos and Teenek present the highest frequencies for the *Arg allele and the lowest frequencies for the *Gly allele (Arg389Gly) compared to European, Asian, and African populations. Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations.