Developing a Clinical Guideline With Embedded Algorithm for the Dosing Frequency of Amoxicillin in Pediatric Group A-Beta Hemolytic Streptococcal Pharyngitis

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Doorn, Derek R
Scholarship & Creative Works @ Digital UNC; University of Northern Colorado
Strep throat; GABHS; Amoxicillin; Strep throat; GABHS; Amoxicillin
textual work description
Group A-beta hemolytic streptococcus (GABHS) pharyngitis, commonly called “strep throat,” is a commonly seen diagnosis in primary care--most commonly seen in individuals aged 5-15 years. Worldwide, 616 million estimated cases of GABHS pharyngitis occur annually. Rheumatic heart disease, which might be a consequence of GABHS pharyngitis, is estimated to cause about 6 million years of life lost annually. In spite of the wide prevalence of the disease, in the current literature, there are differing guidelines regarding treatment of GABHS pharyngitis, specifically with regard to the dosing frequency of amoxicillin. Amoxicillin is a frequently recommended and utilized drug in the treatment of GABHS pharyngitis, often chosen for its palatability and ease of administration. Current literature shows increasing trends toward once daily dosing of amoxicillin in the treatment of GABHS pharyngitis although twice daily dosing was and is still widely utilized. This Doctor of Nursing Practice capstone project evaluated whether a clinical algorithm with embedded algorithm utilizing current evidence-based practice and expert opinions could improve provider proficiency in dosing as well as improve patient outcomes and adherence.