A unique MRI presentation of fungal infection in the brain

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Journal of the College of Physicians & Surgeons of Pakistan, Vol: 24, Issue: 0, Page: 0-0

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Khan, Muhammad B S; Shafqat, Saad; Enam, Syed A
Fungal infection; T2-weighted hyperintense signal; Aspergillosis; Brain; Surgery
article description
ABSTRACTFungal infections of CNS are common in certain geographic locations. MRI with or without contrast is a useful prediagnostictool. However, the findings may sometimes be misleading. In this case report, the authors present unusualimaging findings in the MRI of fungal infection in an immunocompetent host, whereby hyper-intense signals were seen onT2-weighted images and patchy post-contrast enhancement was observed with surrounding edema. These findings weresuggestive of a neoplastic lesion but it was identified as aspergillosis on subsequent histopathology. This unusual MRIfinding of CNS highlights the need to consider fungal infection as a differential diagnosis of all mass lesions on MRI,irrespective of their signal characteristics.