Does Physical Activity Influence Semantic Memory Activation in Amnestic Mild Cognitive Impairment?

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Psychiatry Research: Neuroimaging

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Smith, J. Carson; Nielson, Kristy A.; Woodard, John L.; Seidenberg, Michael; Verber, Matthew D.; Durgerian, Sally; Antuono, Piero; Butts, Alissa M.; Hantke, Nathan C.; Lancaster, Melissa A.; Rao, Stephen M. Show More Hide
Elsevier; e-Publications@Marquette
Exercise; Alzheimer's Disease; Cognition; Psychology
article description
The effect of physical activity (PA) on functional brain activation for semantic memory in amnestic mild cognitive impairment (aMCI) was examined using event-related functional magnetic resonance imaging during fame discrimination. Significantly greater semantic memory activation occurred in the left caudate of High- versus Low-PA patients, (P=0.03), suggesting PA may enhance memory-related caudate activation in aMCI.