The Impact of Sertraline Co-Administration on the Pharmacokinetics of Olanzapine: A Population Pharmacokinetic Analysis of the STOP-PD.
- Citation data:
Clinical pharmacokinetics, ISSN: 1179-1926, Vol: 54, Issue: 11, Page: 1161-8
- Publication Year:
- Repository URL:
- https://escholarship.umassmed.edu/faculty_pubs/877; https://works.bepress.com/anthony_rothschild/134
- Pharmacology, Toxicology and Pharmaceutics; Medicine; Chemicals and Drugs; Pharmacology, Toxicology and Environmental Health; Pharmacy and Pharmaceutical Sciences; Psychiatry and Psychology
Clinical evidence and expert opinion support using a combination of an antipsychotic and an antidepressant when treating major depression with psychotic features. We characterized the impact of sertraline co-administration on olanzapine clearance in psychotic depression using population pharmacokinetic methods.