The Impact of Sertraline Co-Administration on the Pharmacokinetics of Olanzapine: A Population Pharmacokinetic Analysis of the STOP-PD.

Citation data:

Clinical pharmacokinetics, ISSN: 1179-1926, Vol: 54, Issue: 11, Page: 1161-8

Publication Year:
2015
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Repository URL:
https://escholarship.umassmed.edu/faculty_pubs/877; https://works.bepress.com/anthony_rothschild/134
PMID:
25971243
DOI:
10.1007/s40262-015-0275-1
Author(s):
Davies, Simon J.C.; Mulsant, Benoit H.; Flint, Alastair; Meyers, Barnett S.; Rothschild, Anthony J.; Whyte, Ellen M.; Kirshner, Margaret M.; Sorisio, Denise; Pollock, Bruce G.; Bies, Robert R.
Publisher(s):
Springer Nature
Tags:
Pharmacology, Toxicology and Pharmaceutics; Medicine; Chemicals and Drugs; Pharmacology, Toxicology and Environmental Health; Pharmacy and Pharmaceutical Sciences; Psychiatry and Psychology
article description
Clinical evidence and expert opinion support using a combination of an antipsychotic and an antidepressant when treating major depression with psychotic features. We characterized the impact of sertraline co-administration on olanzapine clearance in psychotic depression using population pharmacokinetic methods.